Current funding:

Past funding:

Endothelializing Vascular Graft with Protein Nanoarrays
Objective: Use of protein nanoarrays on a vascular graft for successful endothelialization.
Researchers: David You, Jessica Gamboa, Katherine McCracken, Katrina DeCook, Samir Mohandes
Collaborators: Prof. Marvin Slepian (U Arizona); Prof. Mark Riley (U Arizona)
Current funding: BIO5 Institute; NIH Cardiovascular Training Grant (HL007955)
Past funding: NIH NIBIB (R03EB006754)

A protein nanoarray made by size-dependent self-assembly (SDSA) (left) is installed within a continuous bioreactor to grow HUVECs on it. Saturated, monolayered, yet aligned growth is observed, through both focal adhesion and endocytosis of nanoparticles (middle and right).

"Wire-Guide" Droplet Microfluidics for Reprogrammable and Rapid PCR
Objective: Reprogrammable and rapid PCR for on-site pathogen identification.
Researchers: Dustin Harshman, Christopher Fronczek, Scott Angus, Roberto Reyes
Current funding: QIA; NIH Cardiovascular Training Grant (HL007955); WAESO

Wire-guided rapid droplet mixing (left); Wire-guided quick PCR system (middle); 30-cycle RT-PCR for 2009 H1N1 flu could be finished in 6 min 50 s for 10 uL volume such that gel imaging and gene sequencing could be done in a reproducible and reliable manner (right).

Paper Microfluidics + Smart Phone for Water Quality and Food Safety
Objective: Low-cost smart phone detection of waterborne and foodborne pathogens.
Researchers: Tu San Park, Pei-Shih Liang, Wenyue Li

Smart phone detects immunoagglutination from paper microfluidics (left); Benchtop apparatus used to optimize optical parameters (middle left); Sample is loaded into paper microfluidics by capillary action (middle right); Smart phone captures the image (right).

Last revised: April 18, 2012.