Current funding: NSF; Seoul VioSys; SWEHSC (NIH)
Past funding: WET (NSF); CVTG (NIH); APQA; WSP; Tech Launch Arizona; BIO5 Institute; Desert Tech; WAESO (NSF); NVRQS; NIH; NSF; Arizona Department of Commerce; BMD; University of Arizona
DOTS qPCR
Objective: Handheld PCR system utilizing interfacial tension for pathogen identification.
Researchers: Dustin Harshman, Tu San Park, Tyler Toth
Collaborator: Prof. David Galbraith (U Arizona)


1. Wire-guided droplet manipulator device. 2. Disposable circular cartridge heating module. 3. Wire-guided droplet manipualtions for DNA extraction. 4. Droplet PCR thermocylcing in less than 5 min (for 30 cycles).
Medical diagnostics
Objective: Smartphone biosensors for medical diagnostics
Researchers: Tu San Park, Cayla Baynes, Soohee Cho, Robin Sweeney, Tigran Nahapetian


1. Smartphone attachment for quantifying the band intensities from lateral flow assays. 2. Smartphone-based fluorescence microscope. 3. Paper microfluidics for quantifying bacteria. 4-5. Smartphone application for quantifying the optical signals from paper microfluidics.
Tissue Engineering and Organ-on-a-Chip
Objective: Use of nanostructured surfaces for tissue engineering and organ-on-a-chip applications.
Researchers: Ariana Nicolini, Soohee Cho, Tyler Toth, Collin Gilchrist
Collaborators: Prof. Terrence Monks (U Arizona)

1. Nanostructured ensemble surface, created by e-beam nanolithography and size-dependent self-assembly. 2. Flow-resistant adhesion and proliferation of HUVECs on nanostructured surface. 3 & 4. Linear alignment of fibroblast on sinosoidal wave pattern, towards cellular irrigation.
Air Quality
Objective: Lab-on-a-chip or light-scatter biosensing for air quality.
Researchers: Katherine McCracken


1. Lab-on-a-chip is attached to a smartphone for optical detection. 2. Monitoring H1N1 flu from a mock-up human environment with lab-on-a-chip. 3. CFD simulation for aerosol transport within animal housing. 4. Mie scatter simulation for microbeads and dust particles.
Food Safety and Water Quality
Objective: Lab-on-a-chip for food safety and water quality.
Researchers: Katherine McCracken, Tu San Park, Robin Sweeney
Collaborator: Prof. Kelly Reynolds (U Arizona)


1. Handheld lab-on-a-chip device for detecting foodborne pathogens. 2. E. coli detection from lettuce. 3. Salmonella detection from poultry packaging. 4. Wine tasting on paper microfluidics. 5. Monitoring bacterial contamination from soil with lab-on-a-chip.

Last revised: May 26, 2015.