The Calpain Family of Proteases

Calpain Links Calpain Reagents Storage and Handling Nomenclature Properties of the Calpains 2001 FASEB Conference

The calpain family of proteases consists of 3 well-characterized proteins, -calpain, m-calpain and calpastatin, and approximately 10 other related proteins that have only been found as cDNA's. These molecules have been found in organisms from Drosophila to mammals. This website contains information to assist calpain researchers by providing links to useful reagents, sequence information, other calpain related websites, tips on storage and handling of - and m-calpain and calpastatin and information about calpain conferences.

2007 FASEB Conference
July 14-19, 2007
Snowmass, CO
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Ribbon structure of human m-calpain

Ribbon Structure of Human m-Calpain
taken from
Strobl, S., Fernandez-Catalan, C., Braun, M., Huber, R., Masumoto, H., Nakagawa, K., Irie, A., Sorimachi, H., Bourenkow, G., Bartunik, H., Suzuki, K., and Bode, W. (2000) PNAS, 97(2), 588-592.

For additional information on the three dimensional structure of m-calpain see Hosfield, C.M., Elce, J.S., Davies, P.L., and Jia, Z. (1999) EMBO J. 18, 6880-6889.

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This page was last updated on 24 July 2001 .

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